3D Point Cloud Semantic Segmentation (PCSS) is attracting increasing interest, due to its applicability in remote sensing, computer vision and robotics, and due to the new possibilities offered by deep learning techniques. In order to provide a needed up-to-date review of recent developments in PCSS, this article summarizes existing studies on this topic. Firstly, we outline the acquisition and evolution of the 3D point cloud from the perspective of remote sensing and computer vision, as well as the published benchmarks for PCSS studies. Then, traditional and advanced techniques used for Point Cloud Segmentation (PCS) and PCSS are reviewed and compared. Finally, important issues and open questions in PCSS studies are discussed. A Review of Point Cloud Semantic Segmentation